Pain

Pain Management

Pain conditions like joint and back pain, neuropathy, and migraines can significantly impact daily life. Joint and back pain might come from injuries, arthritis, or overuse, making movement difficult. Neuropathy pain, often caused by nerve damage, can feel like tingling, burning, or sharp stabbing sensations, commonly in the hands or feet. Migraines are severe headaches that can cause throbbing pain, nausea, and sensitivity to light or sound. While these conditions can be frustrating, many treatments are available to help manage pain and improve quality of life.

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Frequently asked questions

What is osteoarthritis?

Osteoarthritis (OA) is the most common form of arthritis, affecting over 32.5 million US adults. Some people call it a degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees. OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or work. Signs and symptoms may include; pain or aching, stiffness, decreased range of motion and swelling of the joints. Risk factors include increased age and obesity.

What is fibromyalgia?

Fibromyalgia is a condition that causes pain all over the body, sleep problems, fatigue, and often emotional and mental distress. People with fibromyalgia may be more sensitive to pain than people without fibromyalgia. Fibromyalgia affects about 4 million US adults, about 2% of the adult population with women being twice as likely to have fibromyalgia as men. Signs and symptoms may include; pain and stiffness all over the body, fatigue and tiredness, tingling or numbness in hands and feet, pain in the face or jaw.

What is peripheral neuropathy?

Peripheral neuropathy is a result of nerve damage that can be described as a stabbing, burning or tingling pain. It often causes weakness, numbness and pain often found in the hands and feet. Peripheral neuropathy can result from a number of factors including injury or autoimmune diseases; however, the most common cause is diabetes.

What are migraine headaches?

Migraines are intense headaches that cause a throbbing or pulsing pain, usually on one side of the head. They can also bring other symptoms like nausea, sensitivity to light or sound, and even vision changes. Migraines can last for hours or even days, making it hard to go about your normal activities. While the exact cause isn’t always clear, there are treatments and lifestyle changes that can help reduce the frequency and severity of migraines, giving you relief and better control over your health.

Topical vs. Oral

Topical applications are known to have a lower-side effect profile when compared with systemic administration. Because the drugs are being applied directly to the skin, there is no first-pass metabolism by the liver. As a result, lower doses of the drugs may be used to get the intended response compared to the oral route. Research has shown topical application may reduce the risk of serious gastrointestinal, renal and cardiovascular adverse events compared with oral treatment options. However, you should always discuss the benefit to risk ratio with your healthcare prescriber.

What is a compounded medication?

One size doesn’t fit all and every patient is unique. Drug compounding is the process of combining, mixing, or altering ingredients to create a medication tailored to the needs of a patient by a pharmacist as the result of a practitioner’s prescription drug order. While compounded medications are not FDA-approved, they serve an important patient need—especially when FDA-approved medication is not available for treatment. Our formulations are made to order in small batches to ensure freshness. The specific ingredients in your compounded formula will depend on your specific concerns and goals. It should be understood that your personal healthcare practitioner will make the final decision.

Are compounded medications FSA & HSA eligible?

Yes! All of our compounded formulations, regardless of ingredients, are eligible for Flexible Spending Accounts (FSA) and Health Saving Accounts (HSA).

References

Cline AE, Turrentine JE. Compounded Topical Analgesics for Chronic Pain. Dermatitis. 2016 Sep-Oct;27(5):263-71. doi: 10.1097/DER.0000000000000216. PMID: 27649348.
Wadsworth LT, Kent JD, Holt RJ. Efficacy and safety of diclofenac sodium 2% topical solution for osteoarthritis of the knee: a randomized, double-blind, vehicle-controlled, 4 week study. Curr Med Res Opin. 2016;32(2):241-50. Doi: 10.1185/03007995.2015.1113400. Epub 2015 Nov 17. PMID: 26506138.
Wiffen PJ, Xia J. Systematic review of topical diclofenac for the treatment of acute and chronic musculoskeletal pain. Curr Med Res Opin. 2020 Apr;36(4):637-650. doi: 10.1080/03007995.2020.1716703. Epub 2020 Feb 3. PMID: 31944135.
Stanos SP, Galluzzi KE. Topical therapies in the management of chronic pain. Postgrad Med. 2013 Jul;125(4 Suppl 1):25-33. doi: 10.1080/00325481.2013.1110567111. PMID: 24547601.
Barton DL, Wos EJ, Qin R, Mattar BI, Green NB, Lanier KS, Bearden JD 3rd, Kugler JW, Hoff KL, Reddy PS, Rowland KM Jr, Riepl M, Christensen B, Loprinzi CL. A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer. 2011 Jun;19(6):833-41. doi: 10.1007/s00520-010-0911-0. Epub 2010 May 25. PMID: 20496177; PMCID: PMC3338170.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Amitriptyline for neuropathic pain and fibromyalgia in adults. Cochrane Database Syst Rev. 2012 Dec 12;12:CD008242. doi: 10.1002/14651858.CD008242.pub2. Update in: Cochrane Database Syst Rev. 2015;7:CD008242. PMID: 23235657.
Maktabi M, Kamali A, Jelodar HT, Shokrpour M. Comparison of Topical and Subcutaneous Bupivacaine Infiltration with Subcutaneous Ketamine on Postoperative Pain in Total Abdominal Hysterectomy. Med Arch. 2019 Feb;73(1):15-18. doi: 10.5455/medarh.2019.73.15-18. PMID: 31097853; PMCID: PMC6445620.
Hershman DL, Lacchetti C, Dworkin RH, Lavoie Smith EM, Bleeker J, Cavaletti G, Chauhan C, Gavin P, Lavino A, Lustberg MB, Paice J, Schneider B, Smith ML, Smith T, Terstriep S, Wagner-Johnston N, Bak K, Loprinzi CL; American Society of Clinical Oncology. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2014 Jun 20;32(18):1941-67. doi: 10.1200/JCO.2013.54.0914. Epub 2014 Apr 14. PMID: 24733808.
Ala S, Alvandipour M, Saeedi M, Mansourifar M, Monajati M, Shiva A. Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial. J Gastrointest Surg. 2020 Feb;24(2):405-410. doi: 10.1007/s11605-019-04147-7. Epub 2019 Feb 19. PMID: 30783957.

Disclaimer

All prescription medications require a valid and complete online consultation prior to approval and final pricing is determined. All compounded medications in the U.S. are considered off-label use. Licensed healthcare practitioners have the ability to prescribe compounds for off-label treatment, if they believe that it is an appropriate course of treatment.

The drug and medical information provided on this website is not meant to cover all adverse effects, drug interactions, warnings, medical uses, directions and precautions. The information provided is a medical resource and the judgment of your physician and/or healthcare practitioner should not be substituted. Premier Pharmacy has made every effort to ensure the information on the website is accurate and current based on present medical literature.

Premier Pharmacy does not make any guarantees regarding the drug and medical information, and does not assume responsibility regarding the content. The drug safety and drug information contained on the website may be time sensitive and should not be utilized as a medical reference beyond the date hereof. The deficiency of a warning for prescription medications and vitamins provided on this website in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient.

If you have questions or concerns about your medications, please do not hesitate to contact us and/or your medical practitioner, including your pharmacist. Compound prescription products have not been tested or approved by the FDA for their intended use. No claims are made as to the safety, efficacy or use of this compound.

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Joint & Back Pain

Neroupathy Pain

Migraine Headaches

What is osteoarthritis?

What is fibromyalgia?

What is peripheral neuropathy?

What are migraine headaches?

Topical vs. Oral

What is a compounded medication?

Are compounded medications FSA & HSA eligible?

References

Disclaimer

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