Topical Pain Formulas
The Topical Pain Formula is a customized prescription blend that may include ingredients such as; a nonsteroidal anti-inflammatory, muscle relaxer, nerve agent, analgesic, and/or local anesthetic that targets the main symptoms of localized pain. It is an odorless gel typically applied to the painful area(s) two to four times daily.
What is the Topical Pain Formula?
The Topical Pain Formula combines prescription ingredients in a proprietary base developed specifically to deliver ingredients through the skin. It uses a unique delivery system designed to increase the permeation of those molecules into and through the skin. It is also not tacky or oily, leaving a light and silky feel on the skin. The Topical Pain Formula is specifically made without fragrance, or gluten.
Topical vs. Oral
Topical applications are known to have a lower-side effect profile when compared with systemic administration. Because the drugs are being applied directly to the skin, there is no first-pass metabolism by the liver. As a result, lower doses of the drugs may be used to get the intended response compared to the oral route. Research has shown topical application may reduce the risk of serious gastrointestinal, renal and cardiovascular adverse events compared with oral treatment options. However, you should always discuss the benefit to risk ratio with your healthcare prescriber.
Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to nerve damage). It has been recommended as a first-line treatment in many guidelines. Neuropathic pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants.
Baclofen is in a class of medications called skeletal muscle relaxants. Baclofen acts on the spinal cord nerves and decreases the number and severity of muscle spasms caused by multiple sclerosis or spinal cord conditions. It also relieves pain and improves muscle movement.
Bupivacaine is in a class of medications called local anesthetics. Bupivacaine is a long-acting numbing agent that blocks the nerve impulses that send pain signals to your brain.
Cyclobenzaprine is in a class of medications called skeletal muscle relaxants. Cyclobenzaprine acts on the spinal cord nerves and decreases the number and severity of muscle spasms. It also relieves pain and improves muscle movement in patients with fibromyalgia.
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain.
Gabapentin belongs to a class of medications called anticonvulsants and has been used to treat nerve pain, such as burning, shooting, or stabbing pain. Gabapentin works by changing the way that nerves send messages to your brain. By altering the way nerves work, gabapentin may reduce your pain.
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain.
Lidocaine is in a class of medications called local anesthetics. Lidocaine is a numbing agent that blocks the nerve impulses that send pain signals to your brain.
Menthol is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). Menthol is known as a counterirritant. It works by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the aches/pains deeper in your muscles and joints.
Frequently asked questions
What is a compounded medication?
One size doesn’t fit all and every patient is unique. Drug compounding is the process of combining, mixing, or altering ingredients to create a medication tailored to the needs of a patient by a pharmacist as the result of a practitioner’s prescription drug order. While compounded medications are not FDA-approved, they serve an important patient need—especially when FDA-approved medication is not available for treatment. Our formulations are made to order in small batches to ensure freshness. The specific ingredients in your compounded formula will depend on your specific concerns and goals. It should be understood that your personal healthcare practitioner will make the final decision.
Are compounded medications FSA & HSA eligible?
Yes! All of our compounded formulations, regardless of ingredients, are eligible for Flexible Spending Accounts (FSA) and Health Saving Accounts (HSA).
What is osteoarthritis?
Osteoarthritis (OA) is the most common form of arthritis, affecting over 32.5 million US adults. Some people call it a degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees. OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or work. Signs and symptoms may include; pain or aching, stiffness, decreased range of motion and swelling of the joints. Risk factors include increased age and obesity.
What is fibromyalgia?
Fibromyalgia is a condition that causes pain all over the body, sleep problems, fatigue, and often emotional and mental distress. People with fibromyalgia may be more sensitive to pain than people without fibromyalgia. Fibromyalgia affects about 4 million US adults, about 2% of the adult population with women being twice as likely to have fibromyalgia as men. Signs and symptoms may include; pain and stiffness all over the body, fatigue and tiredness, tingling or numbness in hands and feet, pain in the face or jaw.
What is peripheral neuropathy?
Peripheral neuropathy is a result of nerve damage that can be described as a stabbing, burning or tingling pain. It often causes weakness, numbness and pain often found in the hands and feet. Peripheral neuropathy can result from a number of factors including injury or autoimmune diseases; however, the most common cause is diabetes.
Is the Topical Pain Formula a narcotic drug?
No, the Topical Pain Formula does not contain any narcotic medications or controlled substances.
How does the Topical Pain Formula work?
The Topical Pain Formula combines multiple prescription ingredients meant to target the main symptoms associated with localized or generalized pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) are standard therapy for osteoarthritis (OA). Topically applied NSAIDs reduce systemic exposure compared with oral NSAIDs. Baclofen is used to treat pain and certain types of muscle stiffness and tightness. Examples of common painful conditions for which baclofen could be used include peripheral neuropathy, low back pain, and neck pain. Amitriptyline is an antidepressant, and antidepressants are widely recommended for treating neuropathic pain. Lidocaine, with its quick onset, and Bupivacaine, with its long duration of action, is not only as a valuable medication for numerous neuropathic pain conditions but also for the management of chronic pain.
When should I see improvement in my symptoms?
Based on research and patient testimonials, you may see improvement as early as 1 hour after applying, but it often takes a few days of continuous use to see the full benefits. Each patient is unique and time frames may differ.
How should I use the Topical Pain Formula?
The Topical Pain Formula is for topical use only. If this medicine gets in your eyes or mouth, rinse with water. Do not apply this medication to your eyelids.
Follow all directions on your prescription label and read all medication guides or instruction sheets.
Wash your hands with soap and water before and after applying the medicine. Do not allow other people to get this medicine on their skin. If this happens, wash the area thoroughly with soap and water.
Apply a thin layer to cover the affected area(s) two to four times per day
Avoid showering/bathing for at least 30 minutes after applying to the treated area(s).
Avoid contact with eyes and mucous membranes. Do not apply to open wounds.
Do not cover treated skin with a bandage or external heat. Bandaging and heat can increase the amount of drug absorbed through your skin and may cause harmful effects.
Avoid wearing clothing over the treated area(s) until the treated area is dry.
Protect the treated area(s) from natural and artificial sunlight.
Wait until the treated area is dry before applying sunscreen, insect repellant, lotion, moisturizer, cosmetics, or other topical medication to the same area you have just treated. Until the treated area(s) is completely dry, avoid skin-to-skin contact between other people and the treated area(s).
Do not use it in combination with other medications in the same class of drugs.
Who should not use the Topical Pain Formula?
Do not start using the Topical Pain Formula if you have a history of hypersensitivity to any of the prescribed ingredients. The prescribed ingredients may include, but are not limited to; NSAIDs (diclofenac, aspirin, ibuprofen, naproxen or others), muscle relaxants (baclofen, cyclobenzaprine, carisoprodol or others), TCAs (amitriptyline, imipramine, mirtazapine or others), or local anesthetics (bupivacaine, lidocaine, prilocaine, benzocaine, tetracaine or others). Please tell your doctor if you are pregnant or thinking about becoming pregnant. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Caution is advised in those patients with renal impairment, liver impairment, cardiovascular disease, or coagulation disorders.
What happens if I miss a dose?
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.
How should I store this medication?
Store at room temperature away from moisture and heat between 68°F to 77°F (20°C to 25°C).
Research has shown, topically applied medications are less likely to cause the same systemic side effects or drug-to-drug interactions as oral medications; however, there is never an absolute zero chance that side effects or drug interactions will not occur. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.
What should I avoid while using the Topical Pain Formula?
This drug product is contraindicated in individuals with a history of sensitivity to any of its components.
Avoid exposure to sunlight or tanning beds. Heat can increase the amount of medication you absorb through your skin.
Do not use cosmetics, sunscreen, lotions, insect repellant, or other medicated skin products on the same area you treat with the Topical Pain Formula.
Use caution when using other products that may contain similar ingredients in the Topical Pain Formula.
What are the common side effects of the Topical Pain Formula?
Although the risk of serious side effects is low when the Topical Pain Formula is applied to the skin, this medicine can be absorbed through the skin.
Common side effects may include application site reactions of:
Skin reactions (dermatitis)
Burning, stinging or warmth
Itching or tingling
Redness, dryness or peeling
Stop using and seek emergency medical attention if you have signs of a heart attack or stroke; chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath or wheezing. Report any symptoms of stomach or intestinal bleeding to your doctor.
Get emergency medical help if you have signs of an allergic reaction: hives, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat. These are not all of the possible side effects of the Topical Pain Formula. For more information, ask your healthcare provider or pharmacist. Tell your healthcare provider if you have any side effects that bother you or do not go away.
What happens if I overdose?
An overdose is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
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